Posted by Quintal on December 23, 2006, at 21:51:30
In reply to Re: pindolol, does it increase the risk of diabeti, posted by linkadge on December 23, 2006, at 15:29:58
>I've read followup studies saying that pindolol does not enhance serotonin release and does not poses significant activity on 5-ht1a autoreceptors.
>These study authors theorized that augmentation must have been through an alternative mechanism.
From what I gather they are suggesting that pindolol acts more as an agonist rather than an antagonist at 5-HT1A receptors.
"Overall, these results indicate that pindolol acts as an agonist rather than an antagonist at 5-HT1A autoreceptors in awake animals. "
I'm not sure how this translates into humans taking MAOIs - maybe there is no interaction between Parnate and pindolol but when I was faced with this dilemma myself I decided to err on the side of caution - I get the impression Parnate is not very forgiving of mistakes with serotegenic meds.
Q
poster:Quintal
thread:715894
URL: http://www.dr-bob.org/babble/20061217/msgs/716032.html