Posted by sdb on December 23, 2006, at 14:15:09
In reply to pindolol, does it increase the risk of diabetis?, posted by medievil on December 23, 2006, at 12:14:36
> i'm very interested in pindolol as an augmentation agent for parnate wich i'm going to take soon
> because
> - it potentiates the antidepressant effect
> - it prevent any hypertensive crisis
>
> but on wikipedia i've read beta blockers could cause diabetis, is this also the case for pindolol?pindolol does not change HDL/LDL ratio significantly. It tends to lower the "bad" LDL cholesterol slightly.
Some betablockers could progress diabetes if there was a diabetes before. But that a betablocker is a trigger to cause diabetes is very unlikely. It could may be more difficult to handle hypoglycemia.
It's very risky to say pindolol can prevent you from a hypertensive crisis. If you take pindolol for the first time there will be an increase in heart rate because of ISA and a vasoconstriction due to strong beta2-blocking properties thus elevating total peripheral resistance. In other words it could make the hypertensive crisis even worse. If you would first take pindolol and wait some time until pindolol has lowered blood pressure and has increased diameter of blood vessels pindolol could prevent you from a hypertensive crisis. MAO's can lower blood-pressure itself and pindolol would lower blood-pressure more by time. If you have a low blood-pressure that could make the pressure too low. A betablocker is not only a med that lowers blood-pressure its an antiarrhythmic. I can only suggest to do experiments with very low dosages of pindolol first. At best discuss that with your doctor.
sdb
poster:sdb
thread:715894
URL: http://www.dr-bob.org/babble/20061217/msgs/715956.html