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Re: hypericum - St. John's wort INTERACTION

Posted by sdb on July 12, 2006, at 13:21:24

In reply to Re: AUC, grapefruit II. }} Squiggles, posted by sdb on July 8, 2006, at 20:00:25

I did some experiments and it seems that hypericum is a very effective inducer of cyp3a.

Thats means: If you take only five pills during five days (of maybe 450mg) the clonazepam or valium maybe working as a placebo pill.

I am not entirely sure and will do some more experiments. But take care combining the hypericum with occasional use of some benzodiazepines.

It is very well known that hypericum does influence other drugs but it is not so well known that hypericum does influence other drugs in psychiatry e.g. benzodiazepines.

Take care

sdb


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