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Re: Link, here's why I'm so focussed on the scienc

Posted by SLS on May 25, 2006, at 6:59:48

In reply to Re: Link, here's why I'm so focussed on the science » linkadge, posted by Larry Hoover on May 24, 2006, at 19:50:58

Perhaps some inpatient studies can be performed prospectively that include daily ratings. Two ratings would be employed; a clinical rating by the observer and a self-rating by the patient. I think a global impression by a trained observer would include ratings of vegetative symptoms that can be associated with the severity of depression. It would be possible that a clinical observer could note a global improvement in a patient's depression at the same time a patient reports an increase in suicidal ideation. This would demonstrate the scenario in which one becomes suicidal as the result of a drug-induced improvement. Likewise, a drug-induced exacerbation would be evident if both observer and patient ratings demonstrate a worsening of depression and an increase in suicidal ideation.

Just an idea.


- Scott

 

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URL: http://www.dr-bob.org/babble/20060525/msgs/648268.html