Posted by Larry Hoover on May 23, 2006, at 18:05:30
In reply to Re: Statistical question on SSRIs - ADDENDUM, posted by linkadge on May 23, 2006, at 17:14:17
> >When a recent study was published, and posted >here, you dismissed the evidence made available >by it. Pre-treatment suicidality was >substantially higher than post-treatment >measures, in the study population.
>
> I dismissed nothing.http://www.dr-bob.org/babble/20060108/msgs/596581.html
It is the only study there is, so far, that looks at pre-treatment and post-treatment (by modern antidepressants) suicidality in the general population. Period. Full stop. All the rest of the data is from clinical trials, or anecdote/case reports.
From the referenced study:
"Before the current controversy, two meta-analyses of data from adult clinical trials found no difference between antidepressant drugs and placebo in risk of suicide during short-term treatment (11, 12). Ironically, those meta-analyses were motivated by ethical concerns about suicide risk in study subjects who were randomly assigned to receive placebo. Because clinical trials typically exclude those at high risk for suicide, some writers have questioned whether suicide risk in clinical trial populations underestimates true risk in those treated for depression."
This is the first, and so far, only study to attempt to answer the question of what happens to real people (not clinical trial subjects, who represent about 7% of the depressed population), in a scientific way. That is all I have ever been saying.
I disagree with your scientific arguments, not your hypothesis.
It is unethical to conduct the studies that you believe would prove your point.
Lar
poster:Larry Hoover
thread:640557
URL: http://www.dr-bob.org/babble/20060520/msgs/647455.html