Posted by linkadge on May 24, 2006, at 19:20:19
In reply to Re: Statistical question on SSRIs - ADDENDUM, posted by Larry Hoover on May 23, 2006, at 18:42:45
>SSRIs have lower suicidality than do >tricyclics. Why aren't you looking there, too?
What is your point? This is a very poor scientific region to even be using words such as "have". We are no longer at the peak of TCA sales, and I don't think that conclusive methodology can be used retrospectively.
Our focus becomes very tight, when under the spotlight. I don't think such a spotlight was ever cast on the TCA's at a time when more significiant evidence could have been gathered.>Healy, after really studying the situation, now >lumps all antidepressants together (I concluded >that before he did).
That would be a safe thing to do. Although, this again makes no sense. The only way such comparisons could be made is if various antidepressants were prescribed with equal frequency, which is not the case.
>If you can't be rigorous, at least describe >your conclusions as being unscientific, or I >shall. SSRIs are, if anything, a lesser risk >than the older drugs they replaced.
I will admit that my conlcusions have been reached without sufficiant conventional evidence. I will also contend that many other conclusions are base upon insufficiant conventional evidence.
>It sucks majorly being the one upon whom the >weight of exception falls. You and I are both >such individuals. Blaming somebody or something >for that is not going to fix anything. Warning >others certainly might.
Contrary to popular belief, I have reached my conclusion based on evidence slightly outside of the boundary of my own experience with these drugs.
>Healy:
>"It would seem likely that explicit warnings >and monitoring in the early stages of treatment >could greatly minimize these hazards."Likely hmm. Well thats one opinion. I suppose even Healy has reason to try and pick up the pieces and reconstruct some foundation. I suppose the drugs would be of higher salvaging value had they demonstrated more efficacy.
Linkadge
poster:linkadge
thread:640557
URL: http://www.dr-bob.org/babble/20060520/msgs/648034.html