Posted by linkadge on April 11, 2006, at 14:45:30
In reply to Re: Parnate is often augmented with Lithium » linkadge, posted by TylerJ on April 11, 2006, at 11:35:51
Yeah, I've been on a lot more lithium than that. I was at 1500mg at one point (used by itself though)
>If lithium can cause serotonin syndrome when >combined w/ maoi's, than surely adding TCA's, >and SSRI's will too, or can too, right?
You mean SSRI + MAOI's ? Definately. Or do you mean lithium + TCA's / lithium + SSRI's?
Lithium + SSRI's can cause serotonin syndrome too, I don't know how common, or how reported it is though.I think serotonin syndrome is due to overactivation of 5-ht1a. It seems that treatment resistant people seem to experience such reactions less, (and this is perhaps due to less responsive 5-ht1a receptors ?)
Sometimes serotonin syndrome is more likely after ECT. I think that ECT causes in increase in the number of 5-ht1 receptors.
Linkadge
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URL: http://www.dr-bob.org/babble/20060408/msgs/631783.html