Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: this is interesting » linkadge

Posted by zeugma on February 21, 2006, at 13:50:19

In reply to Re: this is interesting, posted by linkadge on February 20, 2006, at 16:13:04

> rTMS has been used with some sucess in individuals who are intollerant of medications used in ADD. >>

did you find that your attention/focus was improved while undergoing rTMS?


>
> It has a number of unique biochemical effects, some of which are shared by ECT.>>

then one would expect it to be especially good for the most severe depressions.
>
> It illicits a strong responce in certain areas associated with the regulation of circadian rythem. >>

my circadian rhythms are so disturbed that off medication, they are utter chaos.
>
> It also shows an interesting pattern of receptor alteration. It desensitizes both 5-ht1a/b autoreceptors. It downregulates beta adrenoreceptors. I also think it has some effects on dopamine autoreceptors.>

a while ago (maybe thirty years) there was a beta adrenoceptor hypothesis of AD action. there still is one, apparently, in panic disorder: the only AD's (so called) that are not also antipanic agents are trazodone, bupropion, and buspirone (buspirone is considered an AD by many investigators, and i agree) and none of these down regulate beta adrenoceptor receptors. so perhaps rTMS is an antipanic treatment as well?

(although I wonder if AP's are also antipanic agents, and clonazepam is a most powerful antipanic agent)
>
>
>
> 15 hz also (surprisingly) led to an almost immediate reduction in my headaches.
>
yes, that is surprising. given that the hypnagogic hallucinations/ sleep paralysis I experience with distressing frequency on Provigil feel like electrical shocks sometimes, and leave headaches and insomnia in their wake, I would be most reluctant to apply an electrical device to my skull. that is just my own prejudice.

> rTMS (like ECT) in animals, increases the behavioral sensitivity to stimulants.
>
> (this may be due to 5-ht autorceptor downregulation, since mice 5-ht autoreceptor mutant mice also display an increased behavioral responce to stimulants)
>
i've read that too. the dopamine/serotonin relationship is complex.


-z
> Linkadge
>
>
>
>
>


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:zeugma thread:611154
URL: http://www.dr-bob.org/babble/20060219/msgs/611734.html