Posted by Maxime on April 8, 2005, at 15:45:53
In reply to What is wellbutrin (bupropion) pharmacologically?, posted by sdb on April 8, 2005, at 15:21:16
Hi.
Wellbutrin is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines.
It is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine, and does not inhibit monoamine oxidase.Hope this helps.
Maxime
> I have read it should be a weak noradrenaline/serotonin/dopamine reuptake inhibitor
>
> Most say "pro sexual" effect is caused by increased noradrenaline and dopamine and antidepressant activity also.
>
> In contrast trazodone has pro libido effects (nobody knows why) and pro erection effects (everybody knows) why.
>
> (I personally dont like to much noradrenaline transmission, because of negative experience)
>
> What is true? Does somebody know something or is there some good literature/abstracts?
>
>
poster:Maxime
thread:481676
URL: http://www.dr-bob.org/babble/20050408/msgs/481690.html