Posted by don_bristol on August 2, 2004, at 14:45:42
In reply to Re: How long does MAOI inhibition last with each dose? » don_bristol, posted by King Vultan on July 29, 2004, at 7:51:18
>> Well, the MAO molecule that the MAO inhibitor binds to is permanently rendered useless (in the case of both Nardil and Parnate, which are irreversible MAOIs). However, the body is constantly making new MAO, so what you have is some type of equilibrium forming between the MAO and MAOI. The two main parameters controlling it would be the dosage of the MAOI versus the rate at which the body produces new MAO. Together, these factors govern the degree to which a person's total MAO is inhibited.
>
> Todd <<=======
Todd, if the mechanism is how you describe it (and I am perfectky happy to believe what you write) then why is it worth anyone bothering to take their Parnate as two or three doses a mere few hours apart?
Id the MAOI destroying effect is occuring then I can't see how a few hours makes much difference.
poster:don_bristol
thread:371535
URL: http://www.dr-bob.org/babble/20040730/msgs/373224.html