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Re: How long does MAOI inhibition last with each dose? » don_bristol

Posted by King Vultan on July 29, 2004, at 7:51:18

In reply to How long does MAOI inhibition last with each dose? » King Vultan, posted by don_bristol on July 29, 2004, at 6:02:21

Well, the MAO molecule that the MAO inhibitor binds to is permanently rendered useless (in the case of both Nardil and Parnate, which are irreversible MAOIs). However, the body is constantly making new MAO, so what you have is some type of equilibrium forming between the MAO and MAOI. The two main parameters controlling it would be the dosage of the MAOI versus the rate at which the body produces new MAO. Together, these factors govern the degree to which a person's total MAO is inhibited.

Todd


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URL: http://www.dr-bob.org/babble/20040724/msgs/371954.html