Posted by Caleb462 on May 23, 2003, at 2:43:15
In reply to Re: Starting trimipramine (Surmontil) next week. » Caleb462, posted by SLS on May 22, 2003, at 8:24:01
> Hi Caleb.
>
> Thanks for taking the time to respond.
>
> > > I'll be starting trimipramine (Surmontil) next week. It is a tricyclic antidepressant that is supposed to be sedating. That sucks. Sedation only compounds the problems I have functioning on a day to day basis. Does anyone know if the sedation eventually wears off?
>
> > Overall though, it seems to be quite the mystery drug.
>
> Where on the Internet might I find more information about this drug?
>
> Thanks.
>
>
> - Scottwww.biopsychiatry.com/trimipramine.html
www.biopsychiatry.com/trimipvcloz.htm
and a VERY interesting one...
http://link.springer.de/link/service/journals/00702/bibs/8105002/81050329.htm
"It may be concluded that, like other tricyclic antidepressants studied previously, TRI given repeatedly increases the responsiveness of brain dopamine D2 and D3 (locomotor activity but not stereotypy) as well as <alpha>1-adrenergic receptors to their agonists. A question arises whether the re-uptake inhibition is of any importance to the adaptive changes induced by repeated antidepressants, suggested to be responsible for the antidepressant activity."
Very interesting indeed!
poster:Caleb462
thread:228235
URL: http://www.dr-bob.org/babble/20030520/msgs/228515.html