Posted by stjames on May 23, 2003, at 1:25:50
In reply to Starting trimipramine (Surmontil) next week., posted by SLS on May 21, 2003, at 21:56:31
However, trimipramine is an odd-ball TCA because it does not inhibit the reuptake of serotonin or norepinephrine. Does anyone know how it works? Mysterious.
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> - Scott
I was on it for a year, mostly for sleep and agument of Effexor. I was finding doxipin flattened my affect too much. Flat as a pancake.
I choose Surmontil because it was not as sedating as Doxipin but still enough for good sleep. Also
I liked the fact it did not work with serotonin but (I thought) did with norepinephrine.I found it less sedating, not as anticolinergic or antihistaminic as Doxipin, but that was no surprise as Doxipin is tops in all of these issues.
I liked it, it did augment the Effexor, but I was only taking 100 mgs, which is below the level
at which TCA's kick in for me.I need some sedation, so I liked it, but even for me the sedation was too much at first, but this resolved in 1-2 weeks. Daytime AM sedation was less than Doxipin. Gone were the cravings for sweets, but not carbs. Better affect wise.
None of the nasty perfuse sweating and funky
dreams that I had on Tofrinil.However, back in the good old days, when all we had were TCA's, Doxipin knocked me flat on my
a** for a week, when I started it. Then it kicked in and I was no longer massivly sedated. Quite normal with a normal energy level.As with all the TCA's be carefull about raising the dose at any rate but very slow. Unless you
enjoy being 2D for a few days and sloth like.
poster:stjames
thread:228235
URL: http://www.dr-bob.org/babble/20030520/msgs/228507.html