Posted by Ron Hill on May 22, 2003, at 11:12:21
In reply to Re: Starting trimipramine (Surmontil) next week. » Ron Hill, posted by SLS on May 22, 2003, at 8:21:38
Scott,
> What have you settled on regarding dosing frequency?
As a maintenance dose, 2.5 mg of Enada NADH once per week currently seems to be a fairly good happy-medium for me. I'd like to take 2.5 mg twice or three times a week in order to better treat my atypical depression, but when I increase the dosing frequency, I get irritable. It's a balancing act between depression and a dysphoric mood state. For example, I just went two weeks between 2.5 mg doses, but I fell into an atypical depressive state. The good news is that I took a dose yesterday afternoon and I came out of the depression last night.
Further, thanks to information from Johnj and Larry Hoover, I have begun to experiment with vitamin B3 (niacin, niacinamide) in the 500 mg/day range to treat my irritability. The early results are very promising.
Enough about me; let’s talk about you. As I've told you before, Scott, I recommend that you take 10 mg/day of the sublingual ENADAlert NADH during the acute treatment phase for your atypical depression. If (when) you start to feel irritable, then back off on the dosage and switch to the enteric-coated down-the-hatch Enada NADH. If your atypical depression does not begin to improve within the first week or two of the acute treatment phase, my guess is that it probably is not the answer for you.
Buy a box of the sublingual stuff today, put a tablet under your tongue in the morning, and see what it does. It might not do diddly-squat, but it won't cost you much to try it and it’s not going to hurt you. I agree that you should do this before you begin your trimipramine trial.
Whatever you decide, my well wishings are with you as always.
-- Ron
poster:Ron Hill
thread:228235
URL: http://www.dr-bob.org/babble/20030520/msgs/228329.html