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Re: MAOIs and safety » SLS

Posted by Elizabeth on September 8, 2001, at 21:40:11

In reply to Re: MAOIs and safety » kregpark@yahoo.com, posted by SLS on September 1, 2001, at 7:33:29

> I would have to agree with you. While taking Parnate (120mg), desperation led me to wanting to see what would happen if I were to add a serotonin reuptake inhibitor. I chose Effexor because it had the shortest half-life.

Oh boy. < g > You've got cojones!

> Somewhere in between 15 and 30 minutes, I was totally incoherent and babbling total nonsense.

That sounds familiar!

> Of all the aggressive drug combinations my doctor was willing to consider, it was only MAOIs + SSRIs that he firmly rejected.

With good reason, as you've seen!

> You'll even find reports of serotonin syndrome developing upon the addition of lithium to an SSRI.

Yeah, all kinds of things can cause it. I had a bad episode while taking Effexor XR (by itself).

> This is one combination that I have been very interested to try. Last year, I was about to add Serzone to Parnate + desipramine + Lamictal, but grew shy when one of our posters here described what might have been some sort of dystonic reaction upon adding it to Nardil.

Dystonias can be part of the serotonin syndrome.

-e


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