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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by samantha28 on April 24, 2009, at 21:21:35
Hi, I am currently on 20mg of Abilify and recently started on 100mg of luvox and I feel dizzy, shakey, sleepy and blurred vision.
Are this normal side effects or are these drugs contraindicated?
Cheers
Sam
Posted by Larry Hoover on April 24, 2009, at 22:02:46
In reply to Abilify and Luvox - dangerous interaction, posted by samantha28 on April 24, 2009, at 21:21:35
> Hi, I am currently on 20mg of Abilify and recently started on 100mg of luvox and I feel dizzy, shakey, sleepy and blurred vision.
>
> Are this normal side effects or are these drugs contraindicated?
>
> Cheers
>
> SamYes, there's a definite interaction. Fluvoxamine will inhibit the metabolism of aripiprazole. It's as if you took more Abilify than you normally do, along with the effects of the Luvox. And I haven't considered the receptor-based interactions.
If you can't tolerate the combination, it's contra-indicated.
Lar
Posted by samantha28 on April 24, 2009, at 22:19:58
In reply to Re: Abilify and Luvox - dangerous interaction » samantha28, posted by Larry Hoover on April 24, 2009, at 22:02:46
Hi Larry, thanks so much for your reply. When you say that the Fluvoxamine will inhibit the metabolism of aripiprazole does that mean it will make the aripipazole less effective and stop working? Does it mean I have to take more aripipazole?
I have bipolar disorder and I shouldn't be taking antidepressants alone. I am also having a little bit of shortness or breath.
cheers
Sam
> > Hi, I am currently on 20mg of Abilify and recently started on 100mg of luvox and I feel dizzy, shakey, sleepy and blurred vision.
> >
> > Are this normal side effects or are these drugs contraindicated?
> >
> > Cheers
> >
> > Sam
>
> Yes, there's a definite interaction. Fluvoxamine will inhibit the metabolism of aripiprazole. It's as if you took more Abilify than you normally do, along with the effects of the Luvox. And I haven't considered the receptor-based interactions.
>
> If you can't tolerate the combination, it's contra-indicated.
>
> Lar
>
>
Posted by Phillipa on April 24, 2009, at 23:16:53
In reply to Re: Abilify and Luvox - dangerous interaction, posted by samantha28 on April 24, 2009, at 22:19:58
Samantha how high is your luvox dose? I do know that luvox makes benzos except ativan stronger and dose of other benzos may need to be lowered. Now abilify don't know. Anyway to let your pdoc know what's going on? Love Phillipa
Posted by samantha28 on April 24, 2009, at 23:22:02
In reply to Re: Abilify and Luvox - dangerous interaction » samantha28, posted by Phillipa on April 24, 2009, at 23:16:53
> Samantha how high is your luvox dose? I do know that luvox makes benzos except ativan stronger and dose of other benzos may need to be lowered. Now abilify don't know. Anyway to let your pdoc know what's going on? Love Phillipa
Hi phillipa, I am on 100mg. I think it is normal side effects and I will definitely tell my pdoc about them.
cheers Sam
Posted by SLS on April 25, 2009, at 5:31:41
In reply to Re: Abilify and Luvox - dangerous interaction, posted by samantha28 on April 24, 2009, at 22:19:58
> Hi Larry, thanks so much for your reply. When you say that the Fluvoxamine will inhibit the metabolism of aripiprazole does that mean it will make the aripipazole less effective and stop working? Does it mean I have to take more aripipazole?
>
> I have bipolar disorder and I shouldn't be taking antidepressants alone. I am also having a little bit of shortness or breath.
>
> cheers
>
> Sam
>
> > > Hi, I am currently on 20mg of Abilify and recently started on 100mg of luvox and I feel dizzy, shakey, sleepy and blurred vision.
> > >
> > > Are this normal side effects or are these drugs contraindicated?
> > >
> > > Cheers
> > >
> > > Sam
> >
> > Yes, there's a definite interaction. Fluvoxamine will inhibit the metabolism of aripiprazole. It's as if you took more Abilify than you normally do, along with the effects of the Luvox. And I haven't considered the receptor-based interactions.
> >
> > If you can't tolerate the combination, it's contra-indicated.
If Luvox inhibits the metabolism (slows down the disassembly) of Abilify, the blood levels of Abilify will increase.I have not researched the interaction, so I will defer to Larry Hoover for his expertise in this area.
- Scott
Posted by Zana on April 25, 2009, at 10:26:54
In reply to Re: Abilify and Luvox - dangerous interaction » samantha28, posted by SLS on April 25, 2009, at 5:31:41
I second Scott's nod to Larry. If it's making you dizzy etc., I'd stop the Luvox until you've had a chance to talk with your doc.
Zana
Posted by samantha28 on April 25, 2009, at 16:05:01
In reply to Re: Abilify and Luvox - dangerous interaction » samantha28, posted by SLS on April 25, 2009, at 5:31:41
> > Hi Larry, thanks so much for your reply. When you say that the Fluvoxamine will inhibit the metabolism of aripiprazole does that mean it will make the aripipazole less effective and stop working? Does it mean I have to take more aripipazole?
> >
> > I have bipolar disorder and I shouldn't be taking antidepressants alone. I am also having a little bit of shortness or breath.
> >
> > cheers
> >
> > Sam
> >
> > > > Hi, I am currently on 20mg of Abilify and recently started on 100mg of luvox and I feel dizzy, shakey, sleepy and blurred vision.
> > > >
> > > > Are this normal side effects or are these drugs contraindicated?
> > > >
> > > > Cheers
> > > >
> > > > Sam
> > >
> > > Yes, there's a definite interaction. Fluvoxamine will inhibit the metabolism of aripiprazole. It's as if you took more Abilify than you normally do, along with the effects of the Luvox. And I haven't considered the receptor-based interactions.
> > >
> > > If you can't tolerate the combination, it's contra-indicated.
>
>
> If Luvox inhibits the metabolism (slows down the disassembly) of Abilify, the blood levels of Abilify will increase.
>
> I have not researched the interaction, so I will defer to Larry Hoover for his expertise in this area.
>
>
> - ScottHi Scott, that explains why I became a zombie yesterday. I don't think the safety of taking more than 30mg has been established yet and I took 100mg of lovux so it would have doubled it.
cheers
Samantha
Posted by Zana on April 25, 2009, at 17:42:24
In reply to Re: Abilify and Luvox - dangerous interaction, posted by samantha28 on April 25, 2009, at 16:05:01
Shortness of breath? Have you thought about a quick visit to the ER? Do you know what is causing the shortness of breath? If not, I'd be inclined to stay away from any additional meds until you have been seen by a doctor.
Zana
Posted by samantha28 on April 25, 2009, at 18:20:20
In reply to Re: Abilify and Luvox - dangerous interaction, posted by Zana on April 25, 2009, at 17:42:24
> Shortness of breath? Have you thought about a quick visit to the ER? Do you know what is causing the shortness of breath? If not, I'd be inclined to stay away from any additional meds until you have been seen by a doctor.
>
> ZanaHi Zana, I seem ok now. Initially I was on a dose of 20mg of Abilify then went up to 30mg and I have reduced it today to 10mg with the antidepressant. Thanks so much for your concern hun.
Posted by elanor roosevelt on April 27, 2009, at 22:04:47
In reply to Abilify and Luvox - dangerous interaction, posted by samantha28 on April 24, 2009, at 21:21:35
just Luvox made me ill
can't remember for sure but i think i felt like i had an intense flu every afternoon and was incredibly tiredi lost and entire summer to serzone and luvox
This is the end of the thread.
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