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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by Maxime on February 8, 2006, at 16:54:15
Hi
In 2002 I started what I call a miracle drug - parnate. I was so happy that got rid of my depression and that it wasn't known for pooping out.
According to 2 psychopharmacologists, trileptal is believed to be the culprit in reducing Parnate's efficacy on me. Neither of them really explained why. Does anyone here know?
They tried to take me off the Trileptal in the hospital, but I went hypomanic and psychotic. But I think it's because they took me off it so quickly. I would be willing to wean off the trileptal if it meant that Parnate would work for me again.
I hope someone can tell me why trileptal would affect Parnate.
Maxime
Posted by willyee on February 8, 2006, at 19:39:25
In reply to Parnate and Trileptal - why the clash?, posted by Maxime on February 8, 2006, at 16:54:15
> Hi
>
> In 2002 I started what I call a miracle drug - parnate. I was so happy that got rid of my depression and that it wasn't known for pooping out.
>
> According to 2 psychopharmacologists, trileptal is believed to be the culprit in reducing Parnate's efficacy on me. Neither of them really explained why. Does anyone here know?
>
> They tried to take me off the Trileptal in the hospital, but I went hypomanic and psychotic. But I think it's because they took me off it so quickly. I would be willing to wean off the trileptal if it meant that Parnate would work for me again.
>
> I hope someone can tell me why trileptal would affect Parnate.
>
> Maxime
>Cant tell ya why,but what i can tell you is Tegatrol,you know before they changed its name to trileptal to keep the patent and money was one of the shortest lived combos i tried,i dident like it from day one,and dont think i ever thought twice about trying it again,blah they dident work great for as a team.
Hope that helps even a tiny smudge.
Posted by Maxime on February 8, 2006, at 20:15:20
In reply to Re: Parnate and Trileptal - why the clash?, posted by willyee on February 8, 2006, at 19:39:25
Tegretol and Trileptal are two different drugs... related but different. Trileptal has the same chemical make up as Tegretol except it has an oxygen atom added to it. This helps it have less side effects than Tegretol. Trileptal is the only mood stabiliser that has ever helped me or that I have been able to tolerate. But if getting off meant my Parnate would work again I would do it. Only slowly.
> > Hi
> >
> > In 2002 I started what I call a miracle drug - parnate. I was so happy that got rid of my depression and that it wasn't known for pooping out.
> >
> > According to 2 psychopharmacologists, trileptal is believed to be the culprit in reducing Parnate's efficacy on me. Neither of them really explained why. Does anyone here know?
> >
> > They tried to take me off the Trileptal in the hospital, but I went hypomanic and psychotic. But I think it's because they took me off it so quickly. I would be willing to wean off the trileptal if it meant that Parnate would work for me again.
> >
> > I hope someone can tell me why trileptal would affect Parnate.
> >
> > Maxime
> >
>
> Cant tell ya why,but what i can tell you is Tegatrol,you know before they changed its name to trileptal to keep the patent and money was one of the shortest lived combos i tried,i dident like it from day one,and dont think i ever thought twice about trying it again,blah they dident work great for as a team.
>
> Hope that helps even a tiny smudge.
>
>
Posted by willyee on February 8, 2006, at 20:54:01
In reply to Re: Parnate and Trileptal - why the clash?, posted by Maxime on February 8, 2006, at 20:15:20
Cool wasnt aware of that much difference,you know when u hear things,but thanks clearing that up.
As for ur situation,just keep in mind that although it "might" be the trlpeptal,lets not forget parnate is notrious for pooping out.
Good luck i hope the culprit shows itself .
Posted by Phillipa on February 8, 2006, at 21:20:55
In reply to Re: Parnate and Trileptal - why the clash?, posted by willyee on February 8, 2006, at 20:54:01
Maxime you have always been the best one to know how to change your meds and have them work. And what about the adderal long acting? Fondly, Phillipa
Posted by djmmm on February 8, 2006, at 21:43:16
In reply to Parnate and Trileptal - why the clash?, posted by Maxime on February 8, 2006, at 16:54:15
> Hi
>
> In 2002 I started what I call a miracle drug - parnate. I was so happy that got rid of my depression and that it wasn't known for pooping out.
>
> According to 2 psychopharmacologists, trileptal is believed to be the culprit in reducing Parnate's efficacy on me. Neither of them really explained why. Does anyone here know?
>
> They tried to take me off the Trileptal in the hospital, but I went hypomanic and psychotic. But I think it's because they took me off it so quickly. I would be willing to wean off the trileptal if it meant that Parnate would work for me again.
>
> I hope someone can tell me why trileptal would affect Parnate.
>
> Maxime
>Oxcarbazepine is similar to carbamazepine in that they both induce an array of liver enzymes reponsible for metabolizing most drugs, including Parnate. (they even induce their own metabolism).
Posted by Sobriquet Style on February 9, 2006, at 6:13:47
In reply to Parnate and Trileptal - why the clash?, posted by Maxime on February 8, 2006, at 16:54:15
>They tried to take me off the Trileptal in the hospital, but I went hypomanic and psychotic.
Have you experienced psychosis in the past?...However without it being drug induced or related to the withdrawal of psychiatric medication?
I hope you can find a way to restore Parnates effects.
~
Posted by Maxime on February 9, 2006, at 12:05:32
In reply to Re: Parnate and Trileptal - why the clash?, posted by Sobriquet Style on February 9, 2006, at 6:13:47
Yes, I have experienced psychosis on its own. I am going through it now. I hear voices and I have some visual hallucinations. I try not to feed voices by getting scared or upset. I just tell myself that there is some faulty wiring in my brain. But I do hope they go away soon. I hear voices when my depression is very deep.
Maxime
> >They tried to take me off the Trileptal in the hospital, but I went hypomanic and psychotic.
>
> Have you experienced psychosis in the past?...However without it being drug induced or related to the withdrawal of psychiatric medication?
>
> I hope you can find a way to restore Parnates effects.
>
> ~
Posted by Maxime on February 9, 2006, at 12:09:19
In reply to Re: Parnate and Trileptal - why the clash?, posted by djmmm on February 8, 2006, at 21:43:16
Hi. Can you expand on what you wrote. Are you saying that the Trileptal is reducing the amount of Parnate that my body is metabolising?
Thanks.
Maxime
>
> Oxcarbazepine is similar to carbamazepine in that they both induce an array of liver enzymes reponsible for metabolizing most drugs, including Parnate. (they even induce their own metabolism).
Posted by Maxime on February 9, 2006, at 12:12:23
In reply to Re: Parnate and Trileptal - why the clash?, posted by Phillipa on February 8, 2006, at 21:20:55
> Maxime you have always been the best one to know how to change your meds and have them work. And what about the adderal long acting? Fondly, Phillipa
Hi Phillipa
My pdoc doesn't want me to use the Adderall XR anymore. Drugs like Adderall and Dexedrine give a false sense of well being. He would prefer to correct the chemical imbalance other ways. I could just fill the prescription, but I am trying to work with my pdoc and not go off on my own and change things.
Maxie
Posted by Maxime on February 9, 2006, at 12:16:05
In reply to Re: Parnate and Trileptal - why the clash?, posted by willyee on February 8, 2006, at 20:54:01
Thanks. I didn't know that Parnate was notorious for pooping out. :-( I've heard of people being on it for years. I wish I didn't have such a harsh reaction to Nardil. I think Nardil is probably best MAOI. But I wasn't able to tolerate it. I don't think I would have been able to tolerate the weight gain either.
God this sucks.
Maxime
> Cool wasnt aware of that much difference,you know when u hear things,but thanks clearing that up.
>
> As for ur situation,just keep in mind that although it "might" be the trlpeptal,lets not forget parnate is notrious for pooping out.
>
> Good luck i hope the culprit shows itself .
Posted by ed_uk on February 9, 2006, at 15:38:29
In reply to Re: Parnate and Trileptal - why the clash? » willyee, posted by Maxime on February 9, 2006, at 12:16:05
Hi Maxie
What dose of Trileptal are you on at the moment?
Ed x
Posted by Phillipa on February 9, 2006, at 18:24:30
In reply to Re: Parnate and Trileptal - why the clash? » Maxime, posted by ed_uk on February 9, 2006, at 15:38:29
Maxie I'm so proud of you!!!!! You're doing a good job Fondly, Phillipa
Posted by Maxime on February 9, 2006, at 19:00:42
In reply to Re: Parnate and Trileptal - why the clash? » Maxime, posted by ed_uk on February 9, 2006, at 15:38:29
> Hi Maxie
>
> What dose of Trileptal are you on at the moment?
>
> Ed x450 mg. They increased it in the hospital but they increased it too quickly and I was throwing up on it. So they decided to stop completly. Morons. Then I went psychotic and hypomanic. It's ironic that I was in the hospital and precautions weren't really there when they played around with my meds.
Sorry. Rant over.
Maxime
This is the end of the thread.
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