Posted by djmmm on February 8, 2006, at 21:43:16
In reply to Parnate and Trileptal - why the clash?, posted by Maxime on February 8, 2006, at 16:54:15
> Hi
>
> In 2002 I started what I call a miracle drug - parnate. I was so happy that got rid of my depression and that it wasn't known for pooping out.
>
> According to 2 psychopharmacologists, trileptal is believed to be the culprit in reducing Parnate's efficacy on me. Neither of them really explained why. Does anyone here know?
>
> They tried to take me off the Trileptal in the hospital, but I went hypomanic and psychotic. But I think it's because they took me off it so quickly. I would be willing to wean off the trileptal if it meant that Parnate would work for me again.
>
> I hope someone can tell me why trileptal would affect Parnate.
>
> Maxime
>Oxcarbazepine is similar to carbamazepine in that they both induce an array of liver enzymes reponsible for metabolizing most drugs, including Parnate. (they even induce their own metabolism).
poster:djmmm
thread:607611
URL: http://www.dr-bob.org/babble/20060205/msgs/607748.html