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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by Janelle on February 6, 2004, at 9:08:05
Hi - I know that the SSRI anti-depressants all run the risk of inducing mania in people with BiPolar disorder. I have BP2, and recently I have had episodes of hypomania accompanied by tremendous anxiety and obsessiveness and am wondering of all the SSRI's how *bad* Celexa is for inducing mania? I had been on Paxil for years before it gave me mania and then pooped out on me!
I was taking 50mg a day which is on the high side for Celexa because after mania I go into DEEP incapacitating depression and exhaustion because my body cannot sustain the outpouring of energy and adrenalin during a hypomanic episode. I've lowered the Celexa from 50 to 40 to 30 and do not want to go any lower for fear of losing its antidepressant qualities. I do feel far less hyper on the lower dose of Celexa.
Anyone on Celexa who knows about its potential for inducing mania versus the other SSRI's or anyone who just knows about this issue in general? THANKS!
Posted by HappyGirl on February 6, 2004, at 10:15:34
In reply to Celexa MANIA - help!, posted by Janelle on February 6, 2004, at 9:08:05
Hi:
It's VERY common to induce 'mania/hypomania'after any of SSRIs, such as your case, Celexa.
The best strategy to fight it back is taking/adding 'mood stabilizer,' such as Depakote, Tegretol, even Lithium.
In my knowledge, Depakote is a very first-line mood stabilizer for Bipolar II and work good for 'rapid cycler' that sometime induced by SSRi.
Lithium is generally said to be good for Bipolar I that has more serious form of Bipolar.
Besides this, if you have/experiencing Bipolar, rather than SSRIs, it might be better to take other form of AD, such as Remeron, Wellbutrin and Effexor. The last one, Effexor is not quite SSRI, but seems better than 'pure' SSRI, such as Paxil and Zoloft.
Talk to your pdoc. asap.
H.G.
Posted by crazychickuk on February 6, 2004, at 13:00:10
In reply to Celexa MANIA - help!, posted by Janelle on February 6, 2004, at 9:08:16
I found all ssri's to make me manic... go speak to the phsyc.. get on proper meds like a mood stabilizer
Posted by Karen Moore on February 6, 2004, at 15:58:27
In reply to Re: Celexa MANIA - help!, posted by crazychickuk on February 6, 2004, at 13:00:10
> I found all ssri's to make me manic... go speak to the phsyc.. get on proper meds like a mood stabilizer
>
Ditto. I was diagnosed "anxious depressive" until I took 20mg of Celexa for two weeks and became dysphorically manic. After that I tried 4 other SSRIs. All just made me worse. Now I'm a treatment resisant ultra-rapid cyling bipolar II. Happy happy. Joy joy.
Try a mood stabilizer, BEFORE trying another SSRI/AD.
KM
Posted by CraigD on February 8, 2004, at 0:10:58
In reply to Celexa MANIA - help! » crazychickuk, posted by Karen Moore on February 6, 2004, at 15:58:27
They said it all in the above posts. I'm curious what y'all call ssri-induced hypomania? My Dad and sister are both BP, and I have never been diagnosed, but I get terribly impulsive and this terrible addictive behavior (booze and stimulants)is VERY strong and destructive.
My thoughts get racy and music (just one verse) is constantly playing in my head, however, I don't go without sleep, so my pdoc says that rules out a hypomania. I'm not so sure.
Otherwise, I find the drug helpful in general, although it may be pooping out. I'm supplementing with low doses of tryptophan and everything seems much smoother, less manic. Interesting.
So for those of you experiencing SSRI-induced manias/hypomanias, does this sound familiar?
Posted by Janelle on February 9, 2004, at 18:57:08
In reply to Re: Celexa MANIA - help!, posted by CraigD on February 8, 2004, at 0:10:58
EVERYTHING you have mentioned is what I also experience, and I have been told it's BiPolar2 AND anxiety disorder. It was such a *relief* to hear someone describe exactly what I go through, especially the music. I take Seroquel just for sleeping at night and it's the only thing that gets rid of the darn music. What bugs me is that all my pdocs, past and present, just poo-poo the music, but in my opinion it could be considered a kind of auditory hallucination!
Posted by Minnie-Haha on February 11, 2004, at 22:23:33
In reply to Re: Celexa MANIA - help!, posted by CraigD on February 8, 2004, at 0:10:58
Getting music stuck in your head can be a sign of obsessive-compulsive disorder, too, I think. I often wonder if my "hypomanic" episode (which resulted in my being DXd as BPII -- so never again anti-depressants without mood stabilizers, and I struggle with this DX) was really anxiety coupled with obsessive-compulsive behavior (I have since received an OCD DX, too.)
Maybe anti-anxiety drug/therapy would be worth exploring, instead of anti-depressants? Else, yes, I'd say you need a mood stabilizer, too.
Posted by Minnie-Haha on February 11, 2004, at 22:26:59
In reply to Re: Celexa MANIA - help! » CraigD, posted by Janelle on February 9, 2004, at 18:57:08
Read the post on this site at http://www.dr-bob.org/babble/20020525/msgs/107804.html about "musical hallucinations."
Posted by Lindsay Rae on February 14, 2004, at 14:06:43
In reply to Re: Celexa MANIA - help!, posted by Minnie-Haha on February 11, 2004, at 22:23:33
Huh? I thought everyone has a song stuck in their head at all times? Don't tell me that's just me...I do listen to a lot of music, but if you ask me what song is in my head right now, I'll always have an answer. So now I have OCD? Great.
"Getting music stuck in your head can be a sign of obsessive-compulsive disorder, too, I think. I often wonder if my "hypomanic" episode (which resulted in my being DXd as BPII -- so never again anti-depressants without mood stabilizers, and I struggle with this DX) was really anxiety coupled with obsessive-compulsive behavior (I have since received an OCD DX, too.)
Maybe anti-anxiety drug/therapy would be worth exploring, instead of anti-depressants? Else, yes, I'd say you need a mood stabilizer, too."
This is the end of the thread.
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