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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Ann on April 1, 2000, at 6:58:22
Ever since i started on Celexa, I have noticed that I am
having terrible blood sugar swings, never had problems with
this before, I feel like I have to eat constantly. Have had
blood sugar tests and everything is fine, almost like I have
reactive hypoglycemia, I actually get the sweats and feel
dizzy until I eat, never had this before the Celexa, any one
else experience this, and could the Celexa cause this. Any recommended
websites where I can read about this, thanks,Ann P>S>
I have also experienced weight gain since being on Celexa
because of this.
Posted by Kathie on April 1, 2000, at 18:30:33
In reply to Celexa and blood sugar, posted by Ann on April 1, 2000, at 6:58:22
Ann:
I personally have not ever been on Celexa, but a very close friend is presently on it...since she started it a few weeks ago (around December I think) she has gained an unbelievable amount of weight..she can't fit into clothes she purchased last fall....never in her life has she been so heavy. Consequently her Doctor lowered her dosage, and since doing that she cries alot...her husband died suddenly in May of 1999. I think Celexa does cause weird things to happen to your body.
Kathie
Posted by David Mirtzer on April 3, 2000, at 15:38:37
In reply to Re: Celexa and blood sugar, posted by Kathie on April 1, 2000, at 18:30:33
I have been on Celexa for about six weeks. While I am not diabetic (at least officially), I have monitored my blood sugar ever since getting a fasting 136 about a year ago in a blood test, and then a 132 from a glucose meter. These turned out to be uncommonly high, but by no means unprecedented, readings for me. Since losing over 50 pounds I've only once had a reading over 132 (which was about three weeks after I started taking high doses of Neurontin for Social Anxiety;
I promptly discontined after seeing 82 at night and 140 the nex morning).Anyways, to get to your main question: Celexa has definitely impacted my blood sugar, but in a very good way. My readings are lower (but never under 80), and I don't often have the large nighttime "dawn phenomenon" that I always experienced before, typically *increasing* 15 poinys or more overnight). Lately this benefit seems to be deteriorating. I'm still more stable than before -- especially with regard to lack of overnight rise on most nights -- but the levels are getting back to typical (e.g. 90-100 in the morning). So maybe it's a temporary effect. I don't know how long you've been on the Celexa, but I'd give it a little time to stabilze. (My heartbeat also dropped to 50 beats per minute my first two-three weeks on Celexa. Now it's back up in its usual 70-80 range).I HAVE seen several references in medical journals saying that SSRI's can affect glucose metabolism. But I've also seen that the American Diabetic Association
recommend SSRI's as the first-line AD's for diabetics.By the way, I've LOST a little more weight since being on Celexa, but have had to work a little harder at resisting temptation -- especially sweets. But again, this increase in hunger went away after three or four weeks. Unlike Paxil, Celexa is not known for weight gain.
Hope this helps.
DM
-----
> Ann:
>
> I personally have not ever been on Celexa, but a very close friend is presently on it...since she started it a few weeks ago (around December I think) she has gained an unbelievable amount of weight..she can't fit into clothes she purchased last fall....never in her life has she been so heavy. Consequently her Doctor lowered her dosage, and since doing that she cries alot...her husband died suddenly in May of 1999. I think Celexa does cause weird things to happen to your body.
>
> Kathie
Posted by Leighwit on April 6, 2000, at 12:04:38
In reply to Celexa and blood sugar, posted by Ann on April 1, 2000, at 6:58:22
I think Celexa does have an affect on blood sugar but I hesitate yet to qualify it. I'm a Type I diabetic and have taken every SSRI. I now take Wellbutrin, Celexa, and Aricept. I only added the Celexa a week ago. My blood sugars are swinging a bit, but to what extent I won't know without more data over a longer period of time.
Most SSRI's, in my experience come with a need to adjust my insulin dosages either up or down. Paxil for example, required a 30% increase in insulin and resulted in unacceptable weight gain, so I discontinued it (didn't have much efficacy for me either.)
I'm already getting some benefit from the addition of Celexa (which I've taken in the past but combined with something else) so if I can figure out how to stabilize blood sugars, it will be worth the effort.
It is always difficult to measure the effect of depression symptoms of diabetes itself. Not in terms of behavior (boy -- do people love to focus on behavior when it comes to diabetes management or what?!?!) but in terms of actual biological change(s).
It's now known that 33-50% of people with Type I diabetes develop recurrent major clinical depression.
There's only scant funding to research the connection, unfortunately.
I don't know how any of this affects non-diabetics, hypoglycemics, or people with predispositions to either one of the two types of diabetes.
I do know, however, that people with hypoglycemic episodes should not take SAMe.
Laurie (Leighwit)
Posted by Scott L. Schofield on April 9, 2000, at 11:27:34
In reply to Re: Celexa and blood sugar, posted by Kathie on April 1, 2000, at 18:30:33
> Ann:
>
> I personally have not ever been on Celexa, but a very close friend is presently on it...since she started it a few weeks ago (around December I think) she has gained an unbelievable amount of weight..she can't fit into clothes she purchased last fall....never in her life has she been so heavy. Consequently her Doctor lowered her dosage, and since doing that she cries alot...her husband died suddenly in May of 1999. I think Celexa does cause weird things to happen to your body.
>
> Kathie
It is possible that the crying is actually a symptom of the partial return of depression. If so, this would probably disappear with a return to the higher dosage. I don't think she will find a dosage of Celexa that will both reduce her weight and sufficiently treat her depression.I really don't know too much about SSRIs and weight-gain. I think Prozac may be the least likely to cause this. Check-out some of the numerous archived threads about this topic. They may provide some alternative strategies to combat weight-gain.
- Scott
Posted by Helix on April 17, 2001, at 11:19:00
In reply to Re: Celexa and blood sugar, posted by Scott L. Schofield on April 9, 2000, at 11:27:34
> > I started Celexa 10mg 4 weeks ago for pain management. The only side effect so far has been sexual and it has really helped the pain so I will stay with it for now, but yesterday I had a very weird episode. The night before I had 2 glasses of wine. I know you are not supposed to drink, but most info said a little is ok. In the middle of the night I woke up with a very rapid heart rate and a feeling like I had 10 cups of coffee. Very adrenalized. The heart rate got better, but the edgy feeling lasted the entire day. I was wondering if it could be blood sugar related. I am not diabetic now, but was with each of 3 pregnancies and have glucose intolerance (can't eat lots of sugar on empty stomach or glucose gets high and stays there and sometimes have low blood sugar events). Anyone have anything similar happen? I would love any thoughts - will definately forgo the wine next time.
- Helix
Posted by David Mirtzer on April 17, 2001, at 23:52:11
In reply to Re: Celexa and blood sugar, posted by Helix on April 17, 2001, at 11:19:00
> > > I started Celexa 10mg 4 weeks ago for pain management. The only side effect so far has been sexual and it has really helped the pain so I will stay with it for now, but yesterday I had a very weird episode. The night before I had 2 glasses of wine. I know you are not supposed to drink, but most info said a little is ok. In the middle of the night I woke up with a very rapid heart rate and a feeling like I had 10 cups of coffee. Very adrenalized. The heart rate got better, but the edgy feeling lasted the entire day. I was wondering if it could be blood sugar related. I am not diabetic now, but was with each of 3 pregnancies and have glucose intolerance (can't eat lots of sugar on empty stomach or glucose gets high and stays there and sometimes have low blood sugar events). Anyone have anything similar happen? I would love any thoughts - will definately forgo the wine next time.
> - HelixGlad to hear the Celexa's helping alleviate your pain!
I wouldn't be so quick to conclude the incident you describe was related to the wine or to blood sugar, although I suppose it's possible. Both Celexa, and especially alcohol, can affect glucose levels (usually lowering them for awhile). It was likely a one-time thing, nothing to worry about, although it would be prudent to mention the incident to both your GP AND the doctor who prescribed the Celexa (if that's someone else).
If something like this recurs, it could probably have a large number of causes ranging from a med-induced side effect or interaction, to breakthrough anxiety, to metabolic issues unrelated to the wine and Celexa, to other causes.
Of course, if someone else has had the same experience, they could be more helpful than I.
DM
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In reply to Re: Celexa and blood sugar, posted by David Mirtzer on April 3, 2000, at 15:38:37
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