Posted by undopaminergic on May 1, 2008, at 1:37:37
In reply to Re: Memantine +glutamate ex.toxicty, dramatic reco, posted by utca5utca on April 14, 2008, at 14:45:51
> Two questions for temoigneur and undopaminergic (or anyone else who has taken Memantine):
>
> (1) How rapid is Memantine's onset in relieving stimulant tolerance?
>In my experience, memantine has an onset of action within 1-2 days. However, I currently don't have enough data to differentiate the stimulant-like actions of memantine itself from its potential efficacy against tolerance to (other) stimulants.
> (2) Is it safe to start dosing at the 20mg range and titrate upwards from there?
>The risk of serious adverse effects from starting at 20 mg is low, but the risk of encountering (less serious) side-effects (eg. cognitive impairment) is definitely higher than with a lower starting dose.
>
> Any input regarding my questions on Memantine or alternative methods for curbing my stimulant tolerance (or anything else in general) would be greatly appreciated.
>Examples of other potentially useful drugs are:
* selegiline and rasagiline
* sulpiride and amisulpride (generally low doses only)
* L-dopa and tyrosineOf course, combinations of the above are possible.
poster:undopaminergic
thread:820576
URL: http://www.dr-bob.org/babble/neuro/20080418/msgs/826526.html