Posted by cumulative on July 11, 2008, at 15:40:47
In reply to Re: Memantine +glutamate ex.toxicty, dramatic reco, posted by okydoky on June 20, 2008, at 14:16:27
re: memantine, you should consider ceasing the methylphenidate before adding the memantine (resuming once you've been at the target dose for a few days), and also slowly titrating the memantine upwards (perhaps an increase of 2.5 mg daily) in the interest of avoiding the initial side effects which can include the agitation and tension you described. I experienced these as well early in my use of memantine, but they faded within days of each dose increase.
I currently take 20mg memantine (going to up it to 30mg) and it is a decent antidepressant. On Tuesday or so I should have the chance to trial adding lisdexamfetamine, so we will see if this does well for me. I am attempting to retain the psychostimulant mood boost (short of dumb euphoria), which I feel is probably more therapeutic for me than the later concentrative, but somewhat numbing (IME) effect.
poster:cumulative
thread:820576
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/839280.html