Posted by undopaminergic on March 30, 2008, at 19:34:03
In reply to Re: Memantine +glutamate ex.toxicty, dramatic recovery, posted by bulldog2 on March 30, 2008, at 17:50:36
When I first tried memantine, I took too much, which resulted in a state of impaired thinking (maybe a hint of the dissociative states that NMDA-antagonists can produce), but tolerance quickly developed to that effect, within days. It may be a good idea to take the first doses of memantine at bedtime, or it might ruin your day. It is important not to dismiss it based on initial adverse effects, as I almost did.
Based on the half-life, which is about 3 days, it may be a good idea not to increase the dose more than about 5 mg a week.
poster:undopaminergic
thread:820576
URL: http://www.dr-bob.org/babble/neuro/20080204/msgs/820763.html