Posted by Larry Hoover on March 26, 2005, at 11:48:21
In reply to RE: Liquid Deprenyl » gromit, posted by Elroy on March 12, 2005, at 19:53:26
> I can only report that I've seen posts both ways. Obviously 5mg is 5mg either way, so I think that it boils down to whether or not the liquid version metabolizes faster for some people... and if it does then is that actually even a benefit? Maybe slower metabolizing is better???
The advantage of the liquid is that it is sublingual. The selegiline can directly enter the blood stream across the mucous membranes of the mouth. This bypasses the enteric circulation system, which has massive amounts of the enzymes that break selegiline down. By going straight into the cerebral circulation, more undegraded selegiline can reach the brain, when compared with normal oral dosing. Snorting drugs....why? Straight to the brain. Same sort of rationale.
BTW, that is also why the selegiline patch was developed, to bypass the enteric circulation system, and all its degredatory enzymes.
Lar
poster:Larry Hoover
thread:452259
URL: http://www.dr-bob.org/babble/alter/20050323/msgs/475789.html