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Re: dopamine autoreceptor problem

Posted by linkadge on November 11, 2004, at 16:10:33

In reply to Re: dopamine autoreceptor problem » linkadge, posted by KaraS on November 11, 2004, at 15:16:38

I was taking celexa, but we dropped that.

Still trying to determine the pros and con's of SSRI's

Things should generally go back to the way they were after an SSRI discontinuation. It may take time, but I don't think they may any permanent changes.

I'm not sure of the actual binding of amisulpride. I do know it blocks the d2, and d3 receptors, it addition to blocking dopamine autoreceptors.

This would lead to enhaced dopamine functioning at the d1 receptor, but probably not much increase in dopamine at the d2/d3 receptors.

I would continue with the selegeline and PEA.
If your motivation/energy slowly improves over time then it is likely that the drug is indeed desensitizing the autoreceptor.

Linkadge



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