Posted by DSCH on October 27, 2003, at 9:37:19
In reply to Under-Methylation » Franz, posted by DSCH on October 26, 2003, at 14:50:41
Thanks to Blake Graham for providing me with this diagram.
http://www.thorne.com/altmedrev/fulltext/meth-fig1.jpg
TMG is also known as anhydrous betaine or simply betaine. As you can see it should open up another path for homocysteine to be converted into methionine that is not rate limited by the enzyme methionine synthase (that's how I am interpreting this diagram).
Perhaps my earlier lack of response to TMG was due to a deficiency of magnesium, which is also implicated in ADD (by Healthnotes)(see the diagram: Mg plus ATP convert methionine to SAMe). I began supplementing with Mg before my latest TMG trial.
Healthnotes on Mg...
http://www.gnc.com/health_notes/Supp/Magnesium.htmBlake's website...
http://www.nutritional-healing.com.au/
poster:DSCH
thread:272902
URL: http://www.dr-bob.org/babble/alter/20031023/msgs/273873.html