Psycho-Babble Medication | about biological treatments | Framed
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Re: NMDA Antagonists NOT so good in psych!!

Posted by linkadge on December 22, 2020, at 17:38:34

In reply to Re: NMDA Antagonists NOT so good in psych!!, posted by jay2112 on December 22, 2020, at 13:09:26

There are a few problems with a blanket statement:

Some of the NMDA antagonists (like ketamine) actually increase glutamate in certain brain regions.

Dopamine agonists can reduce glutamate (and hence induce glutamatergic hypofunction resembling schizophrenia).

Lithium has a push pull effect on glutamate (stabilizing glutamate reuptake).

Of course, not all mood disorders are characterized by high glutamate. Also, it also depends on the brain region.

For me, there are times when ritalin helps tremendously. There are other times where I have to stop it.





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