Posted by Christ_empowered on November 3, 2020, at 9:14:30
In reply to Re: Suggestions on treating Tardive Dyskinesia TD?, posted by Lamdage22 on November 3, 2020, at 4:36:48
i don't have solid data on how frequent it is, but...yeah: clozapine can and does cause TD.
in addition, some experts have noticed a definite withdrawal/discontinuation syndrome associated with clozapine, just as one has been noted with those who stop lithium. in both cases, the 'symptoms' can get hellish for a time, often worse than when treatment began. and with clozapine, there seems to be a lot of akathisia popping up after withdrawing the drug, which...
is frightening. clozapine is somewhat unique, but remember: the 'atypicals' are blockbuster drugs, especially in the US. the problems that pop up with stopping clozapine probably overlap with the misery caused by rapid discontinuation (maybe -any- discontinuation?) of any and all neuroleptics, especially the 'atypicals,' so...
lots and lots of people on heavy tranquilizers 'off label.' massive cost$, all around.
ugh. on a personal level, i do think some people should be on a daily tranquilizer, hopefully at the lowest effective dose (something of a pipe dream in the face of 'experts' who want 'dosage optimizations' -- read: as much as the patient can tolerate, often with a side of cogentin to get to the 'right dosage...').
maybe family doctors should handle chronic mental illness? i doubt they could mess it up any worse than the psych industry has...
poster:Christ_empowered
thread:1112392
URL: http://www.dr-bob.org/babble/20201025/msgs/1112429.html