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Re: Trinellix feel like an SSRI? Skeletor

Posted by SLS on July 17, 2020, at 3:03:39

In reply to Re: Trinellix feel like an SSRI? SLS, posted by Skeletor on July 15, 2020, at 7:02:57

> >
> > Trintellix can't be compared to an old SSRI. It can't be compared to a combination of SSRI + anything else (not even buspirone).
>
> Why not?

Vortioxetine (Trintellix) is sometimes called multimodal. It inhibits the reuptake of serotonin/5-HT (like SSRIs) and binds to various receptors:

https://psychscenehub.com/psychinsights/vortioxetine-mechanism-of-action-2/

5-HT7 receptors have been the subject of study more recently with regard to depression.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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