Posted by SLS on July 17, 2020, at 3:03:39
In reply to Re: Trinellix feel like an SSRI? » SLS, posted by Skeletor on July 15, 2020, at 7:02:57
> >
> > Trintellix can't be compared to an old SSRI. It can't be compared to a combination of SSRI + anything else (not even buspirone).
>
> Why not?Vortioxetine (Trintellix) is sometimes called multimodal. It inhibits the reuptake of serotonin/5-HT (like SSRIs) and binds to various receptors:
https://psychscenehub.com/psychinsights/vortioxetine-mechanism-of-action-2/
5-HT7 receptors have been the subject of study more recently with regard to depression.
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