Posted by undopaminergic on May 9, 2020, at 12:16:09
In reply to Re: Amitriptyline and percentages of SERT blockade » undopaminergic, posted by SLS on May 9, 2020, at 11:24:53
> Combining an irreversible MAOI that inhibits MAO-A with a potent serotonin reuptake inhibitor is the most dangerous combination of antidepressants that I can think of. I know this from personal experience (Parnate + single a small dose of Effexor).
>I agree. I was just saying the dose makes the poison. How dangerous is 5 mg sertraline when added to a fully MAO-inhibitory regimen?
> Is tobacco a potent inhibitor of MAO-A?
https://www.ncbi.nlm.nih.gov/pubmed/11343627
Cite: "Smokers have 30-40 % lower MAOB and 20-30 % lower MAOA activity than non-smokers."-undopaminergic
poster:undopaminergic
thread:1109518
URL: http://www.dr-bob.org/babble/20200303/msgs/1110045.html