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Re: Starting Cocaine XR next week

Posted by undopaminergic on April 28, 2020, at 2:27:04

In reply to Re: Starting Cocaine XR next week linkadge, posted by rjlockhart37 on April 27, 2020, at 13:49:09

> the tthing is ..... most of cocaine intake is not thruogh stomach, i read its not well - absored, and its more delivery through sniffing it, or injecting it. I'm serious for some reason i read that it has poor absorbtion when taken orally, i dont know why i read that but thats what i saw.
>
> ... cocaine, it can't be XR because it is not well absorbed, in the intrestines, or whtever through the stomach, ...

Of course, like most drugs, absorption of oral cocaine is less than injected. That doesn't mean bioavailability is 0%. Freud already knew, and reported, that cocaine is orally active.

> ... the best possible way is to keep sniffing, ...

If you overdo that, you can get a perforated nasal septum.

> and even doing that it builds up in your system, even when euphoria is gone, metabolites are still there even though main ones are not producing euphoria.
>

That is like many other drugs. Cocaine itself has a short half-life, but some of the metabolites last longer.

-undopaminergic


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URL: http://www.dr-bob.org/babble/20200303/msgs/1109830.html