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Re: How is everyone? » SLS

Posted by undopaminergic on April 13, 2020, at 6:51:03

In reply to Re: How is everyone? » undopaminergic, posted by SLS on April 11, 2020, at 22:23:32

> Hi, UD.

Hi SLS.

> > > How would you go about switching from Marplan to another MAOI?
>
> > I would go straight from one to another. Less adventurous people would cross-titrate.
>
> Thanks. I appreciate your input.
>

No problem.

> I decided to take only 10 mg of Marplan yesterday. I took none today. I actually feel better. It seems that Marplan was increasing suicidality rather than reducing it. Also, I have been experiencing great fatigue in all of my muscles. Not so much today. I hope it was a side effect.
>

Glad you feel better, whatever the reason.

> > What about clorgyline? Years ago, you said it was good. Why did you stop it?
>
> Clorgyline is easily the most powerful MAOI,

Per unit of weight, or what do you mean?

I think you can get near 100% MAO inhibition with the other potent MAOIs too. Correct me if I'm wrong.

> and was considered to be the most powerful antidepressant in the world when I was being treated with it by the NIH in the early 1990s. However, the NIH stopped giving it to their patients because there were some fatalities involving cardiovascular function. I stopped taking clorgyline before that, though. My response was incomplete, and they wouldn't add a TCA to it.
>

Was it better than the usual (FDA-approved) MAOIs?

-undopaminergic


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