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Re: Dealing with insomnia with desipramine » SLS

Posted by linkadge on April 11, 2020, at 16:19:22

In reply to Re: Dealing with insomnia with desipramine, posted by SLS on April 10, 2020, at 18:31:30

>For many people, clonidine produces profound
>depression.

I don't know if that's universal. In animal models, at least, alpha-2 agonists can reverse stress induced depression (perhaps were the receptors become desensitized leading to excessive catecholamine release).

https://www.sciencedirect.com/science/article/abs/pii/0028390886902327


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