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Dealing with insomnia with desipramine

Posted by TriedEveryMedication on March 30, 2020, at 12:09:05

Hope everyone is holding up ok during this situation.

Desipramine has been the only thing that ever worked for me for being able to focus on tasks and for being able to get things done.

I find that Insomnia with it is horrendous, though. It wasn't always the case. I used to be able to take my dose and sleep through the night maybe 6 hours and jump out of bed ready to go.

The past few times I've been on it, I will wake up at 1 or 2 am and stay away until 6am and then crash again.

I've tried various meds to combat the insomnia and most of them kind of kill the cognitive and attentional benefits of the desipramine. Prazosin maybe worked the best but I still don't get a good night's sleep. hypnotics and trazodone somewhat mess up the benefits of the desipramine.

Without any meds I sleep pretty well.

Any ideas? Any other meds to try instead of desipramine? (I've gone through many other tricyclics and straterra - no luck)




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