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Re: Question..please help re: alzheimer's, depression

Posted by undopaminergic on February 18, 2020, at 11:23:34

In reply to Question..please help re: alzheimer's, depression, posted by jay2112 on February 17, 2020, at 12:08:31

> Hey folks:
> Well, after almost 30 years going around the med and diagnosis spectrum, one med I haven't tried yet is an alzheimer med.One that seems to be studied most for tx resistant depression is memantine. Problem is, that med isn't included in my insurance plan. But, one that is, donepezil, didn't do any better than placebo.
> Does anyone have any experience, or can someone relate?

In my experience, memantine, at sufficient doses, is great for treating some of the most important symptoms of depression, especially mood and apathy. However, you need to be careful, because it can produce mania, with impulsiveness and lack of critical thinking, leading to delusions. Fortunately, this mania subsides when you terminate the drug treatment.

I probably hold the world record in greatest memantine dose taken and survived. This megadose took place due to the impulsiveness associated with the drug. So beware of that.





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