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Re: New US made Marplan now available... SLS

Posted by undopaminergic on February 6, 2020, at 13:37:13

In reply to Re: New US made Marplan now available... undopaminergic, posted by SLS on February 6, 2020, at 10:35:11

> >
> > I'm currently on trimipramine, 100 mg, and it *seems* to be helping with mood. I can't recall having a negative thought in days! I don't seem to have a "mood" disorder any more. I can't say how much that is due to the trimipramine.
> Wow. I'm glad you are feeling better. Have you ever tried nortriptyline?

Trimipramine is my first tricyclic.

In my understanding, nortriptyline is primarily a noradrenaline reuptake inhibitor. Trimipramine is not, but is more like antipsychotics, especially clozapine. I think its antidepressant action is at least partially due to its antagonism of the histamine H2-receptor.





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