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Re: New US made Marplan now available...

Posted by PeterMartin on January 28, 2020, at 3:05:05

In reply to Re: New US made Marplan now available... PeterMartin, posted by SLS on January 22, 2020, at 23:13:05

> I forgot about the peeing thing. I am all-too familiar with that. I had a couple of amazing responses to Nardil, but it never really lasted for very long. I felt 100% normal a couple of times on it, but psychotic mania emerged a few times.

If you go back on Nardil I'd highly recommend trying again to push for Metformin. I know you asked about it and you pdoc wasn't comfortable. Thing is there are some recent studies that suggest it could be helpful for preventing mania (along w minimizing the potential wt gain side effects).

Latest study (albeit in women w PCOS):

There was another good one that I can't find at the moment. The study wasn't reviewing metformin for preventing mood issues, but somehow found that those in the study taking metformin had significantly less mood related hospitalizations over the duration. Need to find that.

Notwithstanding, if you search pubmed or for metformin the recent studies hint that in time it may be repurposed mood issues.

Still early on in my Marplan trial but on a run of good days at the moment. Had nightmares last night which was difficult but today was 2wks off Nardil and on Marplan. Almost certain I'm having some rebound REM. Should subside.




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