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Re: Gabitril and suicidal ideation-UPDATE SLS

Posted by undopaminergic on January 3, 2020, at 11:08:45

In reply to Re: Gabitril and suicidal ideation-UPDATE phidippus, posted by SLS on January 2, 2020, at 20:09:32

> The past 18 months have been hellish for me. Extremely. I got sick and tired of taking Parnate with only a marginal improvement.

Did you try anything to potentiate it? I mean especially (a) neurotransmitter precursors and (b) stimulants, or combinations. (a) would be tryptophan, 5-hydroxytryptophan (5-HTP), phenylalanine, tyrosine, or L-dopa, ideally with a peripheral decarboxylase inhibitor like carbidopa. (b) would be the usual candidates, methylphenidate or dextroamphetamine, but perhaps modafinil (or armodafinil) could be an alternative, and phenylethylamine (PEA) would be an alternative to ampehtamine.

> One aspect of my depression (bipolar) is anhedonia. Parnate doesn't help at all with that. Nardil does, though. For me, I get the impression that Effexor has more potential to improve anhedonia than Parnate.

Have you tried pramipexole (Sifrol or Mirapex)? That was the only anti-anhedonic drug for me.

Do you have apathy, or just anhedonia? Apathy is my main complaint, but for certain I am also interested in relief of anhedonia and cognitive dysfunction. I am not complaining about my mood; I'm not even sure it's depressed.





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