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Re: To SLS - clorgyline and imidazoline

Posted by undopaminergic on January 3, 2020, at 10:52:44

In reply to To SLS - clorgyline and imidazoline, posted by linkadge on January 2, 2020, at 15:52:40

> Hi SLS,
> I recall you once saying that you had a good response to the drug clorgyline.

I recall SLS suggested something along the lines of MAO-A inhibition being more relevant than MAO-B inhibiton with regard to *synaptic* dopamine levels.

I think he may be right, because selegiline, beyond its initial amphetaminergic effect or as a potentiator of phenylethylamine (PEA), or rasagiline, did not have any notable antidepressant effects for me.





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