Posted by zonked on January 28, 2015, at 23:59:05
In reply to Blood levels: Marplan + Lamictal vs Lamictal alone, posted by PeterMartin on January 27, 2015, at 11:08:30
> Hey.
>
> After 5yrs of taking Marplan & Lamictal for Bipolar I/TRD I had to taper off and stop taking Marplan due insurance no longer covering it.
>
> I know Lamictal levels are affected by most other medications and that both Marplan & Lamictal are broken down by the liver.
>
> Is it more likely that ceasing Marplan would lead to a raise in Lamictal blood levels or a lowering?
>
> It's been 2weeks completely off Marplan and while it hasn't been as bad as I thought Ive been quite depressed the last 3 days. At the same time I've noticed I've felt very itchy which I used to experience with Lamictal increases.
>
> I'm just wondering if some of my depression this week could be due to changes in my Lamictal levels and not only the return of MAO. I only take 100mg of Lamictal as in recent trials higher dosages made me extremely fatigued (mid day map required). I took a little extra Lamictal mid day yesterday (maybe 20mg as I broke the tip off a Teva generic) and I do seem to feel better today (still in bed though).
>
> Sorry for rambling but would it be more likely for Lamictal to be more effective/potent after removing Marplan or the other way around?
>
> I know Marplan is uncommon even amongst the MAOIs. Id guess itd be someone similar to taking Nardil&Lamictal to Lamictal alome.
>
> Thanks for any thoughts on this.Have you tried phenelzine (Nardil, which finally, has had a generic for the last several years)? Does your insurance cover it? It's not perfect, but it's been an importent component of my treatment for years now.
Marplan didn't do * for me when I tried it a few years ago..
-z
poster:zonked
thread:1075628
URL: http://www.dr-bob.org/babble/20150102/msgs/1075690.html