Posted by PeterMartin on January 27, 2015, at 11:08:30
Hey.
After 5yrs of taking Marplan & Lamictal for Bipolar I/TRD I had to taper off and stop taking Marplan due insurance no longer covering it.
I know Lamictal levels are affected by most other medications and that both Marplan & Lamictal are broken down by the liver.
Is it more likely that ceasing Marplan would lead to a raise in Lamictal blood levels or a lowering?
It's been 2weeks completely off Marplan and while it hasn't been as bad as I thought Ive been quite depressed the last 3 days. At the same time I've noticed I've felt very itchy which I used to experience with Lamictal increases.
I'm just wondering if some of my depression this week could be due to changes in my Lamictal levels and not only the return of MAO. I only take 100mg of Lamictal as in recent trials higher dosages made me extremely fatigued (mid day map required). I took a little extra Lamictal mid day yesterday (maybe 20mg as I broke the tip off a Teva generic) and I do seem to feel better today (still in bed though).
Sorry for rambling but would it be more likely for Lamictal to be more effective/potent after removing Marplan or the other way around?
I know Marplan is uncommon even amongst the MAOIs. Id guess itd be someone similar to taking Nardil&Lamictal to Lamictal alome.
Thanks for any thoughts on this.
poster:PeterMartin
thread:1075628
URL: http://www.dr-bob.org/babble/20150102/msgs/1075628.html