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Re: Blood levels: Marplan + Lamictal vs Lamictal alone

Posted by ed_uk2010 on January 28, 2015, at 4:10:25

In reply to Blood levels: Marplan + Lamictal vs Lamictal alone, posted by PeterMartin on January 27, 2015, at 11:08:30

> Hey.
>
> After 5yrs of taking Marplan & Lamictal for Bipolar I/TRD I had to taper off and stop taking Marplan due insurance no longer covering it.

Do they cover any other MAOIs? If so, do you plan to switch?

>I know Lamictal levels are affected by most other medications....

By several, but not by most... by any means.

>Is it more likely that ceasing Marplan would lead to a raise in Lamictal blood levels or a lowering?

I couldn't find any evidence that this has been studied. Regarding the related Nardil, I found some evidence to suggest that Nardil does *not* inhibit the metabolism of Lamictal.

>I'm just wondering if some of my depression this week could be due to changes in my Lamictal levels and not only the return of MAO.

It's possible, but to be honest, I think the return of uninhibited MAO is far more likely to be the reason for depressive symptoms appearing.

Take care.

 

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URL: http://www.dr-bob.org/babble/20150102/msgs/1075659.html