Posted by tom2228 on February 24, 2014, at 22:06:11
In reply to Re: protryptiline (Vivactil) safe with MAOI?, posted by Christ_empowered on February 22, 2014, at 7:37:38
First of all, thanks to eveyone for the speedy and lengthy replies, they have been helpful for me as well as having a forum to sift through my mind's contents
rjlockhart:
> a good thing for you from what you wrote: Geodon, it's someways activating....it's not much of a mind duller like zyprexa and seroquel.....
>
> also you may add Namenda.....enhances cognitive function....
>
> none of those will interfere with MAOI'swas on Geodon, up to 80mg for a month this summer in the hospital -- hate it. stimulation was at times "cool" but I felt like it "cracked out" my mania, along w/ cognitive impairment and sedation that I couldn't tolerate. I believe Geodon is contraindicated w/ MAOIs b/c it has SRI (as well as NRI) properties -- I've seen at least 1 case report of fatal serotonin syndrome w/ Geodon and an MAOI.
Luisiana sportsman ---
Wow, that would be so many changes at once. I frequently debate doing things slowly to figure out what's doing what -- I am on a lot of meds after all -- and doing something more like acute care where you change up a lot at once and hope for the best -- as I've been desperate lately.re: Vyvanse been on Vyvanse, not sure I would like it with the Desoxyn. I find my ADHD/ cognition get worse with too much of a stim, and Desoxyn hits the bar pretty well. Would be on dexamphetamine as my 2nd line, but not my cup of tea in general
Thanks for your suggestion about desipramine -- I think I'd rather try that first as it's lower on the muscarinic side-effects. already having trouble urinating with abilify (idk why) on top of the other stimulating meds.
Would take bupropion except it's a potent inhibitor of the CYP 2D6 isoenzyme and would not gel with the desoxyn (or abilify for that matter) -- that was one of the main problems I had with Saprhis unfortunately it just builds up in my system, messes up dosing, and makes me start to feel high -- not good for being in recovery from crystal
Used to take and really liked Ativan -- did a fantastic job on my anxiety where I could just feel OK!!! no longer on it as trying to use other methods to deal with the underlying problems, as well benzos are disinhibiting for me and screw with my priorities -- was conducive to drug use in the past (tho not benzo abuse). might be ok in the future but can do without it for now. nervous about lyrica for same reason -- need to keep my inhibitions for now, I guess. would add it later if necessary -- trying to use neuroleptics to help w/ things and not mask the agitation/irritability/anxiety that is from bipolar, and treat that at the root instead. although ativan did a good for my mood stability actually.
Been on trileptal twice -- does something vivid to my mind, but gives me a lot of anxiety. basically makes me see things so differently and feel so responsible over my life and behavior that I can't breathe, it's almost suffocating. wasn't helping the cycling so we swapped for lamictal this fall.
lamictal is staying at 125mg for a while. it kicked in for mood stabilization/ borderline at 100mg and better now at 125mg. I won't go higher (at least not for now, or so quickly) b/c I get this nasty cognitive impairment that freaked the sh*t out of me 6 years ago on 200mg of the stuff -- first mood stabilizer. o, the early days
What's your beef with strattera? (lol) curious as to why it's not good as an AD as an NRI
Christ_empowered -- ya I've been fluctuating the past week and a half between hating and liking Abilify. hated it this morning but liking it tonight, lol -- I just don't feel as serious about life as I usually am (not good) -- like lack of interest in things including
socializing. Thinking of asking on Saturday for maybe 25mg of desipramine to be taken twice daily for these issues. like I said I liked what Saphris did, and recognized the noradrenergic feeling as something my mood has been missing for years now -- my hypothesis is because of the MAOI suppressing NE function over time. I wonder sometimes if being on Marplan for years (except Nardil and Parnate this fall) is the actual problem instead of the stuff that keeps getting added on top of it.But tonight the cognitive issues w/ Abilify seem better, and I notice I'm functioning more. So I'm going to stick with the Abilify for now, and wait until l adjust more if I need to up to 15mg. If Abilify doesn't work out I'm going to ask for Invega -- I keep debating whether to ask for it this appointment though -- been desperate to get things right.
CE you're right that the lithium w/ neuroleptic makes things tougher; I notice a dip in between the morning and night lithium doses that is in some ways an improvement and in other ways rougher going to stick with both for now.
In the meantime I've upped pramipexole (AM taking the ER actually) to 0.75 two days and it seems to be doing something nice, same with lamictal xr to 125mg (from 100mg) a week ago. Would keep upping the pramipexole but I feel there's something missing (NE?) that I don't want to mask before addressing it. using the pramipexole for bipolar depression and to offset some cognitive effects of neuroleptics (latuda when started it) and of bipolar/ depression in general. like the effect (on-paper) on neurogenesis and neurotrophism.
poster:tom2228
thread:1060964
URL: http://www.dr-bob.org/babble/20140214/msgs/1061273.html