Posted by LouisianaSportsman on February 21, 2014, at 16:28:20
In reply to protryptiline (Vivactil) safe with MAOI?, posted by tom2228 on February 21, 2014, at 13:03:17
Hey, Tom!
Wow, I am enthralled by your thread.
Protriptyline should not cause serotonin syndrome nor have any other undesirable interactions with isocarboxazid. It is one of the most benign TCAs to take concomitantly with an MAOI because it is more of an NRI.
I am diagnosed with BP2, ADHD and possibly BPD myself so I relate to the symptoms you described, predominantly the derealization. Ive never really discussed my derealization symptom with anyone. Would you care to divulge more details about what you experience? (I am also prescribed Lamictal [lamotrigine].)
I switched from Abilify (aripiprazole) to Latuda (lurasidone) about three months ago. Lurasidone is a prodigious AAP, but I believe aripiprazole is slightly superior however, it is not superior enough that I would reverberate due to weight gain. Lurasidone is a miracle in terms of being weight neutral. I have had an almost identical to aripiprazole. I did not experience lethargy on neither AAP.
Honestly, if someone came to me asking for an augmentation to their AD for MDD, Id advocate lurasidone due to its side effect profile and dosing compared to aripiprazole.
Invega (paliperidone), indeed, is the least sedating AAP, but its a tough call whether or not you should switch over or not. Have you considered increasing your methamphetamine dosage? Have you considered that, perhaps, the sedation of aripiprazole will diminish over time?
Also, what is the Mirapex (pramipexole) indicated for? I believe that the dosage is too low to be exerting any therapeutic effect on any of your symptomology.
If youre experiencing sedation on aripiprazole, I do not recommend Seroquel (quietapine) therapy as it is notorious for aggrandizing sedation.
Protriptyline is theoretically awesome on paper; however, there is a reason why it is not prescribed more often severe side effects, e.g. via Ask a Patient, Rating: 3.7/10 [10 reviews] http://www.askapatient.com/viewrating.asp?drug=16012&name=VIVACTIL Pamelor (nortriptyline) on this website scored 3.1/10 [100 reviews]. TCAs are definitely hard to swallow.
In terms of Strattera (atomoxetine) it is the worst possible selection, I consider, of any medication, psychoactive or otherwise.
Tom, I may post a follow-up to this post later because I am going to ponder other possible remedies that might be efficacious for symptom alleviation.
Best wishes to you!
poster:LouisianaSportsman
thread:1060964
URL: http://www.dr-bob.org/babble/20140214/msgs/1060977.html