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protryptiline (Vivactil) safe with MAOI?

Posted by tom2228 on February 21, 2014, at 13:03:17

Anyone know if protryptyline (Vivactil) is safe with an MAOI?

I currently take:

lithium carbonate 900mg
Lamictal 125mg
Abilify 10mg
Marplan 50mg
Deplin 30mg
Mirapex 0.375mg
Desoxyn 15-20mg
levothyroxine 50mcg (for lithium-induced hypo)

but still feeling depressed. main symptoms are apathy, low mood, lack of interest in life and social relationships, feeling flat, anxiety (generalized and social), very neurotic and lack of positive outlook on life and doing the things I need to further my survival. stress, trouble thinking straight and concentrating (perhaps because of interest issues), and irritability, also derealization -- don't always feel like I'm here, like on a strange planet (could be lamictal or depression or BPD)

Meanwhile, diagnoses:

Axis I: Bipolar (I?), ADHD, substance dependence (cannabis and crystal meth, 10 months clean), social anxiety, GAD, some social paranoid
Axis II: borderline, avoidant

Been a week and a half on Abilify as I just switched from 2 weeks of Saphris (was awesome for mood but ran into problems) and 6 months of Latuda. Abilify has taken care of the mania but still a bit irritable/ agitated in background. It has lightened the depression but it is still definitely there.

Abilify has made me extremely sleepy; Saphris was more "sedating" but kept me up and alert all day. Hard to get things done or feel up to it on Abilify. Considering changing to Invega as it's purportedly less sedating and not sure I like the feeling of Abilify, but like the symptom reduction.

Perhaps the Mirapex needs to be brought up as I'm on the lowest dose and it helps. Just avoiding making too many changes at once right now.

Anyway, was considering adding a tricyclic or changing Abilify to or Seroquel (NRI metabolite), but trying to avoid the "bad" type of sedation -- somnolence? -- for me that Abilify produces. I've seen a lot of nortrip with MAOIs on here, but protryptiline is said to be more activating, less sedating. but is it safe?

Any recommendations? Adjustments? Strattera? or is it not good for depression?


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poster:tom2228 thread:1060964
URL: http://www.dr-bob.org/babble/20140214/msgs/1060964.html