Posted by tensor on April 2, 2013, at 11:28:31
In reply to Re: Long-term antidepressant studies, posted by Scars R. Stories on April 2, 2013, at 11:14:42
> Oh, my opinions are based completely on clinical observations - observation about myself and about 10 others. I gained HALF MY BODY WEIGHT (was 120 lbs, became 170) on Remeron. Others gained and could not exercise the weight off, all started craving sweets like mad. ONE person I encountered took 90 mg/night and didn't gain a pound...though she had an eating disorder. And was on so many other meds it would be a puzzle to figure out the sum effect.
> The effects of Remeron felt to me very similar to my experience with Clozaril. It's documented effects on cortisol, insulin, and blood lipids, along with its slowing of the metabolism, now documented based on long-term research (observations) and mechanism of action makes me think that the powers that be are very correct in their reclassification of this medication from antidepressant to sleep aid. And I think that medications that cause type II Diabetes should only be used as a last resort, and with much caution.
> Two rather respected, experienced psychiatrists that I see have both told me that from their observations over many years, they think it is not an antidepressant, and do not like to prescribe it because of its effect on appetite and weight.I'm sorry to hear Remeron didn't work out for you or your friends, fortunately there many others to try. Remeron has been very helpful to me over the years. I think its efficacy as an antidepressant is well established.
http://www.stacommunications.com/journals/diagnosis/2009/09-sep-09/wnicr09-09.pdf
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2809%2960046-5/abstract
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