Posted by jono_in_adelaide on December 11, 2012, at 20:20:06
In reply to Re: Augment Effexor or TCS or MAOI or other?, posted by jono_in_adelaide on December 11, 2012, at 19:53:32
Sertaline and Escitalopram best of "new" antidepressants:
http://www.eurekalert.org/pub_releases/2009-01/l-ass012709.php
Dr Ken Gillman on Effexor
"It is one thousand times weaker than desipramine as a noradrenalin reuptake inhibitor in 'test tube' assays (ie 'in vitro') and more than 100 times less potent than amitriptyline or nortriptyline. This indicates that it may not be justified to classify it as an serotonin and noradrenalin reuptake inhibitor (SNRI) and that additional evidence that it has such actions in humans is required before the proposition of dual action can be accepted with any confidence"
http://www.psychotropical.com/index.php/anti-depressants/135-antidepressants-venlafaxineDr Ken Gillman on SNRI combinations:
"Safe and flexible dual action combinations (of an SSRI with an NRI, e.g. sertraline + nortriptyline) probably allow better efficacy and less side effects"
poster:jono_in_adelaide
thread:1032720
URL: http://www.dr-bob.org/babble/20121130/msgs/1032866.html