Posted by phidippus on September 9, 2012, at 16:16:21
In reply to Re: Nardil 45 mg to 60 mg (worse?) theory. PST PLZ, posted by gilmourr on September 9, 2012, at 15:44:34
>Clomipramine is very interesting but I'm not sure >I can take going back into severe depression again
Are you saying Clomipramine would worsen your depression? I have used it as an augmenter with great success.
I think augmenting the Nardil is the smart choice.
Stimulants aren't the most reliable way of enhancing mood, plus I think they don't go well with MAOIs-though I know they are used. Stimulants work primarily through increasing norepenephrine and dopamine, both of which modulate reward seeking in our brain, indirectly affecting mood.
TCAs act like SNRIs and have robust effects on mood. I would probably have to go with a TCA to augment Nardil therapy.
Atomoxetine and Viloxazine are the only NRIs I know of. Studies don't support Atomoxetine as an antidepressant.
Wellbutrin is the NDRI of choice, but is contraindicated with MAOIs.
You may respond to dopamine well.
Don't forget Mirtazapine. It hits everything!
Eric
poster:phidippus
thread:1025112
URL: http://www.dr-bob.org/babble/20120830/msgs/1025242.html