Re: atomoxetine » SLS

Posted by phidippus on September 11, 2012, at 17:23:01

In reply to Re: atomoxetine » phidippus, posted by SLS on September 11, 2012, at 6:56:32

Atomoxetine increased extracellular levels of NE in the prefrontal cortex 3-fold. Atomoxetine also increased DA concentrations in the PFC 3-fold but did not alter DA in nucleus accumbens or striatum.
Optimal doses of ATM improved PFC cognitive function in monkeys. These enhancing effects appeared to involve indirect stimulation of α(2) adrenoceptors and D(1) dopamine receptors in the PFC.
Desipramine still has an effect on serotonin, whereas Atomoxetine has no effect on serotonin. Also, what I can find in the literature suggests Atomoxetine is a stronger re-uptake inhibitor of Norepenephrine.
Eric

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Re: Nardil 45 mg to 60 mg (worse?) theory. PST PLZ » phidippus SLS 9/9/12
Re: Nardil 45 mg to 60 mg (worse?) theory. PST PLZ gilmourr 9/10/12
Re: Nardil 45 mg to 60 mg (worse?) theory. PST PLZ » gilmourr phidippus 9/10/12
Re: Nardil 45 mg to 60 mg (worse?) theory. PST PLZ » SLS phidippus 9/10/12
Re: Nardil 45 mg to 60 mg (worse?) theory. PST PLZ » gilmourr phidippus 9/10/12
Re: atomoxetine » SLS phidippus 9/10/12
Re: Nardil 45 mg to 60 mg (worse?) theory. PST PLZ » phidippus SLS 9/10/12
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Ondansetron » SLS phidippus 9/11/12
Re: atomoxetine » phidippus SLS 9/11/12
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Re: atomoxetine » SLS phidippus 9/11/12

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