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Re: BDNF connection? » zonked

Posted by SLS on September 21, 2011, at 8:02:06

In reply to Re: BDNF connection? » SLS, posted by zonked on September 20, 2011, at 22:54:01

Hi Z.

> Scott, I notice you haven't taken benzos in a long time or at least since I've corresponded with you.

I have nothing against BZDs, but I prefer to do without them if I can so as not to complicate things too much. Anxiety is not generally a problem with me. However, I have had choppy sleep for about a year. I imagine Nardil contributed to this. Unfortunately, Nardil does not produce total insomnia and suppression of dreaming the same way it did twenty-five years ago. It is scary to think that one can become so brain-dead to no longer experience such potent effects of MAOIs. For sleep, I occasionally combine zaleplon with lorazepam. It works pretty well to get me through the night. I like to think that taking BZDs for sleep every third night helps prevent tolerance.

Coming off of Xanax must be hell if you are in some sort of hypernoradrenergic state.

I don't know what to think of Viibryd and my chances to respond to it. For now, I am treating it as an unknown entity rather than trying to apply the knowledge that it is a SSRI/5-HT1a partial agonist. There must be something more to this drug. People who have tried to replicate the combination of these two properties by taking Buspar and Prozac failed to improve. A mantra of mine is that for every new drug that becomes available, a certain percentage of previously treatment resistant people will respond.

I'll try to check in regularly while I am trialing Viibryd.

What things are you looking to try next?


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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